2-6 kD

Mid-size MW Compounds

As the development of therapeutics has progressed through the years, the purification of mid-size molecules have taken an important role in separations science. These applications range from early polypeptide hormones such as calcitonin, to the trend of longer-chain synthetic peptides such as exenatide, to an emerging class of therapeutic oligonucleotides, to the growing global need for improved versions of recombinant insulin.

This growing class of therapeutics with 2 to 6 kD molecular weight requires a family of silica gels with a range of pore sizes, particle sizes and endcapping to optimize your purification.

silica gel for purification of recombinant peptides

‘Just Right’ for Mid-Size Molecules

DAISOGEL offers one of the widest ranges of high-performance spherical silica gels, all manufactured under our renowned quality system. With pore sizes ranging from 100 Å to 300 Å, various carbon loadings, and unique endcapping, we surely can provide a silica gel that will help you sustain purity for your mid-size therapeutic.

Bulk Silica Gels with 100 – 300 Å Pore Sizes

The following DAISOGEL products are suitable for the purification of products with molecular weight between 2 –6 kD. Click on a pore size to learn more.

Recommended Pore Size (Å)
ODS Phase C8 Phase C4 Phase APS Phase
PK Series 100 100 100
P Series 100 120
200
120
200
HP Series 100 100
RPS Series 100
120
200
300
BP Series 120
200
BIO Series 120
200
300
120
200
300
120
200
300

Did you know?

DAISOGEL offers technical support to optimize your mid-size molecule separation.