BULK SILICA
C4 Phases: SP-C4-NP
C4 is one of the workhorse reverse phases for chromatographic purifications. But not every C4 is equivalent—and in some cases, the chromatographer may in fact want a unique selectivity for a special application.
We understand that you need special tools in your purification toolbox, which is why we continue to pioneer the next generation of reverse phases. To that end, we have launched a groundbreaking C4 silica gel with a completely different separation mode: a non-endcapped version of C4 which permits separation that is dominated by silanol interactions.
Typical Applications
Our non-encapped, ‘Black Box’ phase
Small Molecules
Synthetic Peptides
Standard Peptides
In the “Standard Peptides”, SP-100-8-C4-NP works by far the best. All six peptides are separated with a different elution order, Leu-Enkephalin elutes before Neurotensin.
7 Basic Drugs
Another example is shown in the analysis of “Seven Basic Drugs”. SP-100-8-C4-NP delivers good separation topped with a different elution order for Diphenhydramine, Lidocain and Diphenidol.
Available in 100 Å pore size and 8, 10 and 15 μm particle sizes
Ordering Information (Bonded Phase SP-C4-NP)
| Product Name | Pore Size (Å) | Particle Size (µm) | Pore Volume (mL/g) | Surface Area (m2/g) | % of Carbon |
|---|---|---|---|---|---|
| SP-100-8-C4-NP | 100 | 8 | 1.1 | 450 | 10.0 |
| SP-100-10-C4-NP | 100 | 10 | 1.1 | 450 | 10.0 |
| SP-100-15-C4-NP | 100 | 15 | 1.1 | 450 | 10.0 |
Did you know?
This novel combination of hydrogen bonding capacity from silanols combined with hydrophobicity from the C4 is only the beginning. Additional “black box” non-endcapped phases are coming soon!