SYNTHETIC PEPTIDES

Coming Back Into Favor

As their name implies, synthetic peptides are chemically synthesized on a solid phase using Fmoc or Boc chemistry. While synthetic peptides have much in common with traditional small molecules, their higher selectivity and potency coupled with their tendency to be naturally degraded in the human body make peptides a more attractive therapeutic modality. They have demonstrated significant potential in the treatment of a variety of metabolic and oncological disorders; owing to their proven pharmacological value and favorable safety profiles, the demand for peptide drugs is on the rise.

Peptide therapeutics have kept pace with scientific innovation by expanding into new indications and molecular targets. No longer limited to 10 amino acid chains, many therapeutic peptides in development are up to 40 amino acids long – adding to purification challenges.