SYNTHETIC PEPTIDES

Coming Back Into Favor

As their name implies, synthetic peptides are chemically synthesized on a solid phase using Fmoc or Boc chemistry. While synthetic peptides have much in common with traditional small molecules, their higher selectivity and potency coupled with their tendency to be naturally degraded in the human body make peptides a more attractive therapeutic modality. They have demonstrated significant potential in the treatment of a variety of metabolic and oncological disorders; owing to their proven pharmacological value and favorable safety profiles, the demand for peptide drugs is on the rise.

Peptide therapeutics have kept pace with scientific innovation by expanding into new indications and molecular targets. No longer limited to 10 amino acid chains, many therapeutic peptides in development are up to 40 amino acids long – adding to purification challenges.

silica gels for purification of synthetic peptides
C18 Phases
A Range of Options

A Range of Options

DAISOGEL offers many silica gel products suitable for synthetic peptide purifications. Our ODS-P Series is your first choice for synthetic peptides, as it provides superior performance and the highest surface areas (450 m2/g) for high loadability. Our popular ODS-RPS Series is a workhorse with 17% carbon loading. The ODS-BIO Series offer a wide pH operating range. The ODS-BP Series offers unique endcapping technology.

Go to ODS phases

Bulk Silica Gels for Synthetic Peptide Purification

The following DAISOGEL products are suitable for the purification of synthetic peptides. Click on a pore size to learn more.

Recommended Pore Size (Å)
ODS Phase C8 Phase C4 Phase APS Phase
PK Series 100 100 100
P Series 100 120
200
HP Series 100 100
RPS Series 100
120
200
BP Series 120
200
BIO Series 120
200
120
200
120
200

Did you know?

The global therapeutic peptides market is expected to grow from $28B in 2019 to $39B in 2024.