BULK SILICA

C18 Phases: SP-ODS-BIO

As recombinant peptides, oligonucleotides, and proteins continue to be a driving force for new pharmaceuticals, DAISOGEL has launched the BIO Series of spherical silica gels.

ODS-BIO Series is suitable for purification of small peptides, microbial proteins (insulin) and oligonucleotides requiring wide pH range applications. With its significant improvement in durability against acidic and alkalic resistance, ODS-BIO Series can be used for an extended period in acidic mobile phase conditions and regenerated with solvents containing NaOH.

wide pH range C18 silica gel

Typical Applications

Wide pH range and pore size range for small, mid, and large molecules

Small Molecules

Synthetic Peptides

Recombinant Peptides / Insulin

Ultra High Purity

The BIO Series silica gels are equipped with a narrow particle size distribution, ultra high purity totally spherical base silica gel, and high density bonding for performance under extreme pH conditions.

ODS-BIO Series Selection Chart

Pore Size (Å)Molecular Weight Range (Da)Example Application
120Low (<2000)Small peptides
200Mid (2000-6000)Insulin
300High (>6000)Proteins

Available in 120, 200, and 300 Å pore sizes and 5 μm, 10 μm, 15 μm, and 20 μm particle sizes

Ordering Information (Bonded Phase C18)

Product NamePore Size (Å)Particle Size (µm)Pore Volume (mL/g)Surface Area (m2/g)% of Carbon
SP-120-5-ODS-BIO1205130020
SP-120-10-ODS-BIO12010130020
SP-120-15-ODS-BIO12015130020
SP-120-20-ODS-BIO12020130020
SP-200-5-ODS-BIO20051.120015
SP-200-10-ODS-BIO200101.120015
SP-200-15-ODS-BIO200151.120015
SP-200-20-ODS-BIO200201.120015
SP-300-5-ODS-BIO30050.91008
SP-300-10-ODS-BIO300100.91008
SP-300-15-ODS-BIO300150.91008
SP-300-20-ODS-BIO300200.91008

Helpful Tip

ODS-BIO Series is recommended as your first choice when screening unknown mid or large MW compounds. Move on to C8 or C4 phases if less retention is required.

Other DAISOGEL Products in BIO Series