BULK SILICA

C8 Phases: SP-C8-BIO

As recombinant peptides, oligonucleotides, and proteins continue to be a driving force for new pharmaceuticals, DAISOGEL has launched the BIO Series of spherical silica gels.

C8-BIO Series is suitable for purification of small peptides, microbial proteins (insulin) and oligonucleotides that are too strongly retained on ODS phases. With its significant improvement in durability against acidic and alkalic resistance, C8-BIO Series can be used for an extended period in acidic mobile phase conditions and regenerated with solvents containing NaOH.

wide pH range C18 silica gel

Typical Applications

Wide pH range and pore size range for small, mid, and large molecules

Small Molecules

Synthetic Peptides

Recombinant Peptides / Insulin

Ultra High Purity

The BIO Series silica gels are equipped with a narrow particle size distribution, ultra high purity totally spherical base silica gel, and high density bonding for performance under extreme pH conditions.

C8-BIO Series Selection Chart

Pore Size (Å)Molecular Weight Range (Da)Example Application
120Low (<2000)Small peptides
200Mid (2000-6000)Insulin
300High (>6000)Proteins

Available in 120, 200, and 300 Å pore sizes and 5 μm, 10 μm, 15 μm, and 20 μm particle sizes

Ordering Information (Bonded Phase C8)

Product NamePore Size (Å)Particle Size (µm)Pore Volume (mL/g)Surface Area (m2/g)% of Carbon
SP-120-5-C8-BIO1205130012
SP-120-10-C8-BIO12010130012
SP-120-15-C8-BIO12015130012
SP-120-20-C8-BIO12020130012
SP-200-5-C8-BIO20051.12008
SP-200-10-C8-BIO200101.12008
SP-200-15-C8-BIO200151.12008
SP-200-20-C8-BIO200201.12008
SP-300-5-C8-BIO30050.91006
SP-300-10-C8-BIO300100.91006
SP-300-15-C8-BIO300150.91006
SP-300-20-C8-BIO300200.91006

Helpful Tip

C8-BIO Series should be evaluated for your mid or large MW compounds that retain too strongly on Bio Series ODS phases.

Other DAISOGEL Products in BIO Series