2-6 kD

Mid-size MW Compounds

As the development of therapeutics has progressed through the years, the purification of mid-size molecules have taken an important role in separations science. These applications range from early polypeptide hormones such as calcitonin, to the trend of longer-chain synthetic peptides such as exenatide, to an emerging class of therapeutic oligonucleotides, to the growing global need for improved versions of recombinant insulin.

This growing class of therapeutics with 2 to 6 kD molecular weight requires a family of silica gels with a range of pore sizes, particle sizes and endcapping to optimize your purification.

‘Just Right’ for Mid-Size Molecules

DAISOGEL offers one of the widest ranges of high-performance spherical silica gels, all manufactured under our renowned quality system. With pore sizes ranging from 100 Å to 300 Å, various carbon loadings, and unique endcapping, we surely can provide a silica gel that will help you sustain purity for your mid-size therapeutic.

Bulk Silica Gels with 100 – 300 Å Pore Sizes

The following DAISOGEL products are suitable for the purification of products with molecular weight between 2 –6 kD. Click on a pore size to learn more.

	Recommended Pore Size (Å)
	ODS Phase	C8 Phase	C4 Phase	APS Phase	Phenyl Phase
PK Series	100	100	100	—	—
P Series	100	—	120 200	120 200	—
HP Series	100	100	—	—	100
RPS Series	100 120 200 300	—	—	—	—
BP Series	120 200	—	—	—	—
BIO Series	120 200 300	120 200 300	120 200 300	—	—
NP Series	—	—	100	—	—

Did you know?

DAISOGEL offers technical support to optimize your mid-size molecule separation.